SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF SUBSTITUTED BENZOXAZOLE DERIVATIVES
*D.Maruthamuthu, Shameela Rajam, Christina Ruby Stella, Ranjith, Rajakumar
Abstract
A Series of some novel benzoxazole compounds were synthesized and
evaluated for anti-microbial activity. The reaction of o-aminophenol
with dicarboxylic acid yield substituted benzoxazole. The title
compounds were synthesized by treating substituted benzoxazole with
oxalic acid,cinnamicacid, succinic acid,phthalic acid,salicylic
acid.Their structures were confirmed by IR, 1HNMR, and 13CNMR.
Anti-microbial activity against staphylococclus aureus was studied for
the synthesized compounds.
Keywords: Benzoxazole, o-aminophenol, dicarboxylic acid, Antimicrobial.
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