WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

AMELIORATIVE EFFECTS OF ALLIUM CEPA IN ETHANOL INDUCED NEUROPATHIC PAIN IN RATS

Prabhjot Kaur, Tapan Behl*, Shweta Bhardwaj, Heena Goel

Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage and is induced by noxious stimuli. The sensation of pain is a protective mechanism for the body and it initiates nociceptive reflexes. Neuropathic pain is defined as pain initiated or caused by a primary lesion or dysfunction in the nervous system, either central nervous system (CNS) or peripheral nervous system (PNS). As the onset of neuropathic pain may be delayed after nerve injury, pain may still be present after healing is complete. This makes proper diagnosis and early treatment difficult. Moreover, neuropathic pain commonly occurs as a secondary symptom in diseases like diabetes, cancer and herpes zoster infection; it may also occur with treatments such as chemotherapeutics or cytotoxic drugs. The various first line drugs available for neuropathic pain (such as gabapentin, pregabalin, duloxetime, tricyclic antidepressants etc.,) are not found to be fully effective in the treatment. Henceforth, alternative treatments are being researched upon. Murraya koenigii is one such possible alternative, which is considered in the present study and is successfully found to provide positive results towards the prevention and maintenance of peripheral neuropathic pain due to its anti-oxidant, anti-inflammatory and cellular calcium modulatory action.

Keywords: allodyna, hyperalgesia, neurological disorder, demyelination, neuropathy


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More