Abstract

ANALYSIS OF QUANTITATIVE INDICATORS OF LEADING CLINICAL SIGNS OF ICTERIC CHOLESTASIS IN OPTIMIZATION OF ITS THERAPY EFFICIENCY

Lola Izzatilloyevna Makhmudova* and Nilufar Sharipovna Akhmedova

Abstract

Assessing the competence of the information potential of quantitative indicators of the leading clinical and biochemical signs of icteric cholestasis (ICh) and optimizing its therapy. The material for the study was quantitative indicators of clinical signs of cholestasis of 66 patients (18 male persons, and other persons of female) with chronic diffuse liver diseases. Indicators leading clinical signs – (SICH) jaundice and pruritus were quantified using a Likert scale. The number of points was allocated to assess the range from 1 to 3, and it depended on the severity of clinical signs leading SICH. The results showed that the information potential of quantitative indicators of clinical signs SICH was quite competent to differentiate into individual grades. At the same time, among other clinical symptoms of cholestasis were the most informative indicators of jaundice. From the perspective of clinical practice, it is claimed SICH division into separate independent gradation. Leading clinical symptoms SICH possess sufficient information potential to delineate it’s severity for certain types.

Keywords: Icteric Cholestasis, Main Clinical Signs, Jaundice, Pruritus, Evaluation.