Abstract

METFORMIN: CURRENT CONCEPTS AND FUTURE PERSPECTIVES

Disha Shetty, Veena Nayak*

Abstract

Metformin, a biguanide is a preferred oral hypoglycemic agent for type 2 diabetes. It has also found to be beneficial in delaying the occurrence and progression of complications of diabetes Metformin is also being used as an off label drug for polycystic ovarian syndrome, antipsychotic induced weight gain, obesity and gestational diabetes mellitus. Research to study its role in malignancies is ongoing. The pleiotropic effects of metformin definitely will lead to multiple indications for metformin in the near future. This review focusses on the current status and future perspectives of metformin.

Keywords: Metformin, hypoglycemic agent, weight gain.