Abstract

PHARMACOVIGILANCE: AN OVERVIEW

Megha Anna Varghese*, Jasmy E. S., Sharon Ann Varghese, Anjana Baby, Sara Yeldhos and Shindya B.

Abstract

Pharmacovigilance is defined by WHO as the science and activities relating to the detection, assessment, understanding and prevention of the adverse effects of drugs or any other possible drug-related problems. Adverse drug reactions (ADRs) are ranked as the top 10 leading causes of mortality and morbidity in the world. Pharmacovigilance is concerned about evaluating and monitoring the safety of medicine in clinical practice to improve patient's safety. Pharmacovigilance promotes safety and efficacy of the drug. The preliminary essential steps of pharmacovigilance is the reporting of suspected adverse drug events. PV evidence of medicine related problems like poor quality drugs, treatment failure, drug interaction. The Pharmacovigilance exertion in India is organized by The Indian Pharmacopoeia Commission and conducted by the Central Drugs Standard Control Organization (CDSCO). The fundamental aim of PvPI is to collect data, method, analyze it and provide necessary interventions to Health care professionals to minimizing the potential risks associated with the drug or blood and blood products. Pharmacists contribute to the drug safety by preventing, identifying, documenting, and reporting of ADRs.

Keywords: Pharamacovigilance, adverse effects, importance, PvPI.