Abstract

REVIEW ON GENOMIC STRUCTURE, PATHOGENESIS, AND RECENT ADVANCE STRATEGIES FOR DIAGNOSING AND TREATMENT OF NOVEL COVID 19

Abhijeet R. Gaikwad* and Dr. K. S. Salunke

Abstract

Corona virus illness 2019 (COVID-19) may be a type of pneumonia with associate uncommon outbreak in city, China, in December2019, that is prompted by suggests that of severe acute respiratory syndrome coronavirus two (SARS-CoV-2). Therefore, fast and a correct identification of pathogenic viruses performs an essential perform in choosing terrific treatments, saving people’s lives and preventing epidemics it's essential to determine a fast-standard diagnostic take a look at for the detection of the infectious disorder (COVID19) to stop subsequent secondary spread. The emergence of SARS-CoV-2 has been marked because the 1/3 introduction of a noticeably infective coronavirus into the human population once the severe acute respiratory syndrome corona virus (SARS-CoV) and therefore the Middle East respiratory syndrome corona virus (MERS-CoV) within the 21st century. during this minireview, we offer a quick introduction of the overall features of SARS-CoV-2 and discuss current information of molecular immune pathologic process, which can be useful in providing novel insights and attainable therapeutic aims for combating the SARS-CoV-2 infection. polymerase chain reaction (PCR) is considered a gold standard test for the molecular identification of microorganism and bacterial infections with high sensitivity and specificity. isothermal nucleic acid amplification is taken into account to be a extremely promising candidate technique because of its fundamental advantage in fast procedure time at constant temperature while not thermocycler operation. a range of improved or new approaches even have been developed. This review summarizes the presently accessible detection methods for coronavirus nucleic acid.

Keywords: Coronavirus; SARS-CoV-2; MERS-CoV; SARS-CoV; pathogenesis, Nucleic acid detection, PCR-Based methods, Isothermal nucleic acid, five recent treatment for COVID 19.