Abstract

A REVIEW ARTICLE ON: CORONA VIRUS THE SILENT KILLER

Nilesh N. Shinde, Sushil S. Kore*, Swapnil J. Barde and Rushikesh R. Waghmare

Abstract

In December 2019, the outbreak of the 2019 novel coronavirus disease (COVID-19) in China spread worldwide, becoming an emergency of major international countries. SARS-CoV-2 infection causes various severe respiratory illness similar to severe acute respiratory syndrome coronavirus. The transmission has been given with incubation time between 2-14 days, providing its transmition via droplets, contaminated hands or surfaces. Early diagnosis, quarantine, and supportive treatments are essential to cure patients. We therefore reviewed the literature on all available information about the epidemiology, diagnosis, isolation and treatments of COVID-19. Treatments, including antiviral agents, chloroquine and hydroxychloroquine, corticosteroids, antibodies, convalescent plasma transfusion and vaccines, will be discussed in this article. Additionally, registered trials about treatment were listed to develop approaches for the current urgent demand for therapy.

Keywords: COVID-19; Pandemic; Diagnosis; Isolation; Remdesivir; Clinical trials.