Abstract

SCIENTIFIC ANALYSIS OF VAJRA KANDI CHENDURAM A SIDDHA FORMULATION TOWARDS ITS SAFETY, PHARMACOLOGICAL ACTION AND PROPOSED BENEFITS IN THE MANAGEMENT OF COVID-19

Saravana Siva P.*, Sivanantha A., Sasivel S., Siva Kumar G. and Shanmugam M.

Abstract

Vajra kandi chenduram is a Siddha formulation has been widely used especially among traditional Siddha practioners towards the management of several acute and chronic ailments ranging from fever to chronic inflammatory disorders and immune mediated diseases. This literature review of Vajra kandi chenduram involves the scientific analysis of Lingam (Cinnabar), Veeram (Mercuric perchloride), Pooram (Hydragyrum subchloride), Rasa sinduram (Red sulphide of Mercury) that are ingredients as well as Annabedhi chenduram that can be used as an adjuvant. The search results confirm the antipyretic, anti-inflammatory, antioxidant activity of its ingredients. Based on this search and the clinical experiences of Siddha physiscians in the management of earlier epidemics, these results has derived a hypothetical claim that Vajra kandi chenduram through its antipyretic and anti-inflammatory properties can be effective in inhibiting the inflammatory mediators and cytokine storm of COVID-19 which is a major cause of serious lung complications. Therefore this formulation can be considered as a safe and effective supportive therapy in the absence of any specific target treatment measures.

Keywords: Vajra kandi chenduram, COVID-19, Siddha, Antipyretic, Anti-inflammatory.