Abstract

A REVIEW ON POTENTIAL PROPERTIES AND THERAPEUTIC APPLICATIONS OF GRAPE SEED EXTRACT

Bharat Kwatra*

Abstract

Grape seeds are rich in proanthocyanidins which have been shown to possess potent free radical scavenging activity. Grape seeds are a complex matrix containing 40% fiber, 16% oil, 11% proteins, and 7% complex phenols such as tannins. Grape seeds are rich sources of flavonoids and contain monomers, dimers, trimers, oligomers, and polymers. The monomeric compounds includes (+)-catechin, (−)- epicatechin, and (−)-epicatechin-3-O-gallate. Studies have reported that grape seeds exhibit a broad spectrum of pharmacological properties against oxidative stress. Their potential health benefits include protection against oxidative damage, and anti-diabetic, anticholesterol, and anti-platelet functions. Recognition of such health benefits of proanthocyanidins has led to the use of grape seeds as a dietary supplement by the consumers.

Keywords: Grape seeds are rich in proanthocyanidins which have been shown to possess potent free radical scavenging activity.