World Journal of Pharmaceutical Research (WJPR) has indexed with various reputed international bodies like :

WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.453

ICV : 90.8

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	All	Since 2020
Citation	8502	4519
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Abstract

SYNTHESIS AND EVALUATION OF PHARMACOLOGICAL ACTIVITIES OF SOME 1,3,4-OXADIAZOLES,1,2,4-TRIAZOLES POSSESSING s-TRIAZOLE MOIETY

*D.Kumudha, T.Kalavathi, R.Venkatanarayanan, R.R.Reddy

Abstract

Starting from substituted benzohydrazides, 2-(3-mercapto-5- substituted phenyl-4H-1,2,4-triazol-4-yl) acetohydrazide[6a-d] were prepared. From [6a-d], a series of new 1,3,4-oxadiazoles [9a-d], 1,2,4- triazoles [10a1-a2 – 10d1-d2] were synthesized and evaluated for anticonvulsant, CNS depressant activity and Neurotoxicity.

Keywords: 1, 3, 4-oxadiazole, 1, 2, 4-Triazole, Anticonvulsant, CNS depressant activity, Neurotoxicity

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