Abstract

THERAPEUTIC EFFECTIVENESS OF THE SIDDHA IMMUNO MODULATORY POLYHERBAL FORMULATION NELLIKAI LEGIYAM AGAINST COVID-19 PANDEMIC- A REVIEW

Siva Lakshmi S.*, H. Vetha Merlin Kumari, S. Mohan and R. Meenakumari

Abstract

In Siddha system of medicines, Nellikai legiyam is significantly used as immunomodulatory drug. The current outbreak of coronavirus (COVID-19) is one of the immunosuppressive or immunomodulatory diseases. According to WHO, the serious symptoms of COVID-19 are shortness of breath, chest pain and loss of speech. This review article focuses on the phytochemicals and pharmacological activities of prior study work on each of its herbal ingredients i.e., Phyllathus emblica (Nellikkai vatral), Zingiber officinalis (Chukku), Piper nigrum (Milagu), Piper longum (Thippili), Piper longum root (Thippili Moolam), Carum copticum (Omam), Syzygiyum aromaticum. Linn (Lavangam), Elattaria cardamomum. Maton (Elarisi), Illicium verum (Thakkolam), Cuminum cyminum. Linn (seeragam), Coriandrum sativum. Linn, (Kothumalli), Maranta arundinacea (Koogai neer), Glycirrhiza glabra (Athimathuram), Embelia ribes. Burn.f (Vayuvidangam). Nellikai legiyam is concluded to have Immunomodulatory, antioxidant, anti-inflammatory and antimicrobial action after analysis of the bioactive constituents and pharmacological action for the treatment of COVID-19.

Keywords: COVID-19, Nellikai legiyam, Siddha, Immunomodulator drug.