World Journal of Pharmaceutical Research (WJPR) has indexed with various reputed international bodies like :

WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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ICV : 90.8

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Abstract

TO DEVELOP VALIDATED METHOD OF SALICYLIC ACID BY UVVISIBLE SPECTROSCOPY AS IMPURITY IN PHARMACEUTICAL DOSAGE FORM

Parul Bisht*, Manoj Kumar, Pratiush Saxena and Dr. Atul Kumar Gangwar

Abstract

A method to form a UV-Visible active derivative of Salicylic acid was developed. The method was based on the reaction of salicylic acid, forming a colored derivative, which was UV-Visible active. The method was used to analyze pharmaceutical dosage form for trace amount of salicylic acid using UV-Visible spectrophotometer. The formed derivative exhibits maximum absorbance at λmax= 505nm. The method was validated in the range of about 10-90μg/ml.

Keywords: Salicylic acid, Ferric Chloride regent, UV-Visible spectrophotometer.

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