Abstract

ROLE OF ANTIOXIDANTS IN DIABETES AND ITS COMPLICATIONS: AN OVERVIEW

Malavika Ashok, Bency Bernard, Archana J. R., Surabhi S. V., Silvia Navis*, Prasobh G. R. and Grace N. Raju

Abstract

Hyperglycemia advances auto-oxidation of glucose to develop free radicals. The free radical formation past the rummaging capacities of endogenous antioxidant defenses brings about macrovascular and microvascular complications. Cell reinforcements, for example, Nacetylcysteine, Vitamin C and α-Lipoic Acid are powerful in diminishing diabetic inconveniences, demonstrating that it might be valuable either by ingestion or through dietary supplementation. Be that as it may, while antioxidants are demonstrating fundamentals in the examination of oxidant stress-related diabetic pathologies and in spite of the clear potential value of a substitution treatment, the safety and viability of antioxidant supplementation in any future treatment, needs to be built up.

Keywords: Hyperglycemia, auto-oxidation, NAC, vitamin C, ?-Lipoic Acid.