Abstract

AN OVERVIEW ON SARS-COV-2 OUTBREAK: PANDEMIC OF THE CENTURY

*Ahire Saurabh Nandkumar, Panchave Rutuja Tukaram, Dr. Mahaparale Sonali, Khadse Shubham and Pagar Roshani Rajendra

Abstract

Whole world is facing new invisible enemy SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2). This world health crisis begins in December 9, when SARS-CoV- 2 emerged at seafood wet market of Wuhan, Hubei province, South China and then it rapidly spread throughout the whole world. Virus then declare as a Public health emergency of International concern by WHO (World Health Organization). This coronavirus generally affects the lower respiratory tract and manifests as pneumonia in humans. The incubation period is around 2-14 days. Many patients are asymptomatic and they may act as carrier of virus some of them may be super spreaders. Diagnosis of disease is done by RT-PCR test by using nasopharyngeal swabs. CT of chest is also abnormal in those with no symptoms or mild disease. Currently there is no any cure or vaccine is available to treat this SARS-CoV-2 and by using some drug like remdesivir, hydroxychloroquine the severity of disease is decreases. WHO and CDC advice to keep social distancing and avoid public places and close contact with infected person. This article is all about the publicly available information related to this new virus and summarize the knowledge about the pathogen and the current pandemic. In this literature review, the introduction of SARS-CoV-2, condition all over the world, pathogenesis, symptoms, treatment and management and prevention strategies all are reviewed.

Keywords: SARS-CoV-2, RT-PCR, pneumonia, coronavirus.