Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF MEDHYA CHURNA–W.S.R. TO CEREBRAL PALSY

Dr. Miral Dobariya*, Harisha C. R., Shukla V. J., Dr. K. S. Patel and Dr. V. K. Kori

Abstract

Cerebral Palsy is the most common motor disability in children. Cerebral Palsy (CP) is defined as a group of permanent disorders of the development of movement and posture, causing activity limitations that are attributed to non-progressive disturbances occurred in the developing fetal or infant brain. Medhya Churna is an Anubhoota Yoga used in the department of Kaumarbhritya, IPGT & RA in the management of Neuropsychiatric disorders since longtime. The present study was carried out to standardize the finished product Medhya Churna to confirm its identity, purity and quality. All attempts have been made to evaluate its Phamacognostical and physico-chemical profile. Medhya Churna was analyzed through Pharmacognostically and also it was analyzed through qualitative and quantitative analysis of physicochemical parameters. High Performance Thin layer Chromatography study (HPTLC) was also studied. Study of drug, Coloenchyma cells, Cork cells, Starch grains, Covering trichome, Crystal fibers, Pitted vessels etc were present characteristic features of observed. Physicochemical analysis shows loss on drying 8.09% w/w, Ash value is 14.60%w/w water soluble extract is 17.02% w/w, alcohol soluble extract is 10.05%w/w and PH is 6.5(5% aqua solution). High Performance Thin Layer Chromatography (HPTLC) showed 6 spots at 254 and 7 spots at 366 nm. This shows the presence of certain definite constituents in the Medhya Churna and is helpful for the easy separation of these constituents.

Keywords: Cerebral Palsy, HPTLC, Medhya Churna, Pharmacuetics, Pharmacognosy