Abstract

FORMULATION AND EVALUATION OF NUTRACEUTICAL CINNAMON TABLET BY WET GRANULATION METHOD

*Chaudhari Nikhil Suresh, Dr. J.Y. Nehate, Kale Akshada Sudhakar, Badgujar Vaishnavi Chandrashekhar and Bhusare Nilam Dilip

Abstract

The objective of study was to formulate and evaluate the nutraceutical tablets by the wet granulation methods and to study the effect of it on the various parameters such as dissolution studies. The nutraceutical tablet was formed by mixing the lactose and cinnamon and sodium saccharine by geometric mixing and the 5% starch paste was added as binder. The granules were prepared and dried in air. Tablet was compressed. The compressed formulation were subjected to all studies such as appearance, thickness, weight variation, hardness and friability. The friability, weight variation, hardness, thickness, dissolution of tablet was found in acceptable range. The in-vitro release of eugenol from optimized nutraceutical tablet was found to be 88.1%. Significant result was obtained from the studies. Tablet was found to be stable during handling and shows more promising results than direct compression methods. The current investigation clearly found that the wet granulation do not affects the in-vitro release of eugenol from the cinnamon. So wet granulation method has scope in the nutraceutical cinnamon tablet formulations.

Keywords: Wet granulation, Eugenol, Nutraceutical, In-Vitro release.