Abstract

A CASE REPORT ON GUILLAIN BARRE SYNDROME WITH HISTORY OF HIV AND SPINAL TUBERCULOSIS

Azgari Begum, Syeda Maimoona Maqsood, Sania Mehveen, Lubna Muzaffar Hussain and Dr. S. P. Srinivas Nayak*

Abstract

Background: Guillain-Barre syndrome is a rare autoimmune disorder in which the immune system attacks healthy nerve cells in your peripheral nervous system. Its occurrence throughout the world with a median annual incidence of 1.3 cases per population of 100000, with men being more frequently affected than women. Case presentation: A 47 y/o female was brought to the hospital with complaints of weakness, paralysis of both lower limbs since 1 week. The physical findings found were febrile, increased heart rate, weakness and numbness in both lower limbs causing paralysis with areflexia. Conclusion: Guillian barre syndrome is a rare autoimmune disorder as it causes weakness, numbness and eventually paralysis of the whole body. Diagnosis can be made by progressive motor weakness and muscle inability to respond to stimulus I.e. areflexia and the history of HIV possess the risk factor in this patient. Current treatment includes plasmapheresis, immunoglobulin therapy and additionally analgesics and anticoagulants in pharmacological therapy. In non pharmacological therapy, physiotherapy is required.

Keywords: Guillian barre syndrome, Human immune deficiency virus, paralysis, areflexia, plasmapheresis, immunoglobulin therapy.