Abstract

PHARMACOGNOSTICAL (INGREDIENTS IDENTIFICATION) AND PHARMACEUTICAL ANALYSIS OF VYAGHRI TAILA –AN AYURVEDIC POLYHERBAL FORMULATION FOR PRATISHYAYA

Neethu Kesavan*, D. B. Vaghela, Harisha C. R. and V. J. Shukla

Abstract

Background: Nasya (Nasal administration of drugs) is one among Panchakarma Chikitsa which is specifically indicated for Urdwajatru Gata Roga. Vyaghri Taila is a Sneha Kalpana indicated for Nasya Chikitsa especially in Nasagata Roga (Diseases of nose). In present study, it has been used for Virechana Nasya in Dushta Pratishyaya (Chronic Sinusitis). Objective: To analyze the raw drug authentication, pharmacognostical and physicochemical parameters of Vyaghri Taila. Materials and Methods: Drug identification and authentication was done by Pharmacognostical study i.e. morphological features, organoleptic characters and powder microscopy of drugs. Physicochemical evaluation such as specific gravity, acid value, saponification value, iodine value, refractive index and HPTLC were carried out of the prepared drug. Results: Pharmacognostical study of ingredients showed presence of epicarp cells, lignified stone cells, simple trichomes, stellate trichomes and stone cells of Vyaghri. Pitted vessels, rhomboidal crystals, simple fibers and brown content of Dhanti was observed. Mesocarp cells, stone cells, black debris and simple starch grains of Maricha and Stone cells, oil globules and fibres of Pippali were noted. Stomata, trichomes, starch grains and oil globules of Tulsi were noted. Annular vessels, oleoresin content and starch grains of Vacha also noticed . On Pharmaceutical analysis, Refractive index noted at 400 C, 1.484, Specific gravity at room temp. at 320 C 0.958, Acid value 3.4, Iodine value 12.312, Saponification value 85.6, Loss on drying noted 0.32 were noted. High performance thin layer chromatography at 254 and 366 nm resulted into 9 and 7 spots respectively. Conclusion: Raw drug identification and authentication has been done and evaluation of physicochemical parameters has been carried out.

Keywords: Vyaghri Taila, Dushta Pratishyaya, Pharmacognosy, Pharmaceutics,