Abstract

DRUG UTILIZATION EVALUATION OF PRE−OPERATIVE ANTIMICROBIALS USED IN SURGERY DEPARTMENT AT A TERTIARY HOSPITAL

Mahima Jose*, Sanisha V. Soman, Deepa Koshy, Abiya Susan Shibu, Nisha Pothen, Dr. Roshiny Thankam James

Abstract

The use of antimicrobial agents need to be evaluated since misuse of antimicrobials may lead to increased adverse effects, resistance to antimicrobials, making illnesses more serious, and increasing expenses of health services. The aim of this study was to assess the Drug Utilization Evaluation of pre-operative antimicrobials used in the surgery department at a tertiary care hospital. This prospective observational study was carried out with 181 patients who had undergone various surgeries in the General Surgery department of Muthoot Healthcare Kozhencherry from November 2018 to May 2019. In this study it was found that the majority of surgeries were performed in males and the age group of 61-80 years. Most of the subjects had undergone incision and drainage. The most commonly and efficiently used preoperative antibiotic and antiprotozoal agent was the fixed dose combination of Cefoperazone- Sulbactam (56.35%) and Metronidazole respectively. Drug utilization evaluation of antimicrobials are essential as it highlights the importance of assessing optimal drug use and provides a strong basis for therapeutic decision making.

Keywords: ANTIMICROBIALS; DUE; PRE-OPERATIVE; CEFOPERAZONE?SULBACTUM; METRONIDAZOLE.