Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF TRIPHALADI KWATHA GANDUSHA

B.S.M.M. Sooriyaarachchi*, Rajaguru R.M.C.D, D. B. Vaghela and Harisha C. R.

Abstract

Introduction- Gingivitis is a reversible oral disease that refers to gingival inflammation, occurs widely in mouth affecting both children and adults. According to the ancient Ayurvedic texts, this disease can be correlated with Shitada which is under the heading of Dantamulagataroga which are 15 in number mentioned by Acharya Susruta. Spontaneous bleeding from gums which are foul-smell, blackish, moistened, softened, and succumbed to necrosis and suppurated, one after the other would be the signs and symptoms of Shitada. Triphaladi Kwatha is one of the drugs which were mentioned by Acharya Sushruta for Gandusha in Shitada. Till date no published data is available regarding evaluation of Triphaladi Kwatha. Methods-Final product was subjected to Pharmacognostical and physico-chemical analysis such as microscopic study, loss on drying, ash value and pH etc. Results and Discussion- Pharmacognostical study showed the presence of contents such as; Epicarp cells of Haritaki, Lignified Stone cells of Haritaki, Trichomes of Bhibhitaka, Rosette cells of Bhibhitaka, Lignified Scleroids of Amalaki, Scalariform vessels and Oleoresin content of Shunthi, Lignified Epicarp cells of Sarshapa, Starch grains of Musta, Lignified Fibres and Scleroids of Rasanjana etc. Preliminary physico-chemical analysis showed that the loss on drying value was found to be 7.38% w/w, pH 3.5, Ash value 7.26% w/w, Water soluble extract 34.11% w/w and, Methanol Soluble Extract 29.16%w/w. High Performance Thin Layer Chromatography (HPTLC) showed 6 spots at 254nm and 1 spots at 366nm. Conclusion-The present work was carried out to standardize the finished product of Triphaladi Kwatha in terms of its identity, quality and purity. Pharmacognostical and Physico-chemical observations revealed the specific characters of all active constituents used in the preparation.

Keywords: HPTLC, Pharmacogonosy, Pharmaceutical.