Abstract

BONE TURNOVER BIOMARKERS OF ORAL FLUIDS: A REVIEW

Dr. Suchetha A.*, Dr. Aparna Suraj N., Dr. Apoorva S. M., Dr. Divya Bhat, Dr. Sapna N. and Dr. Darshan B. M.

Abstract

Diagnostic techniques conventionally used to assess periodontitis are clinical and radiographic measurements. These methods are inherently limited only to a historical perspective and lacks to identify and provide knowledge about the highly susceptible individuals who are at a greater risk for future bone loss.[1] Biomarkers not only diagnose the disease but also predicts the risk of future disease activity by simple and affordable means.[2] Bone remodeling is a process of bone formation and resorption. Bone turnover markers (BTMs) assess the rate of bone turnover. BTMs detected in GCF (gingival crevicular fluid) or saliva of patients with periodontitis provides information about the extent of alveolar bone involvement and predicts the susceptibility of individuals towards risk of bone loss. Hence, detection of these biomarkers, aids in diagnosis of periodontitis at an early stage and also reduces the disease severity and progression.[1]

Keywords: Bone turnover biomarkers, periodontal disease, peri-implant disease.