Abstract

EMULGEL: AN ENORMOUS APPROACH FOR TOPICAL DELIVERY OF HYDROPHOBIC DRUGS

Maneesh Banyal* and Swati Joshi

Abstract

In NDDS, emulgel technology is presently of attentiveness to the pharmaceutical researchers because of their fundamental prospects and topically having property of dual controlled release i.e. gel as well as emulsion. In topical delivery system, a major constraint of gels is their incapacity to the deliver hydrophobic drugs. To control this constraint of gels and successful incorporation of hydrophobic drugs, emulsion based approach is being used. Emulsion is gelled by mixing it with a gelling agent which makes it stable and controlled release system. Due to gelling capacity of polymers can be used as thickeners and emulsifiers for a stable emulsion by increasing viscosity of aqueous phase and decreasing the surface and interfacial tension. Due to access oily bases and lack of insoluble excipients, emulgel integrate better drug release for a topical drug delivery system.

Keywords: Emulgel, Gelling agent, hydrophobic drugs, Topical drug delivery.