Abstract

COMPARITIVE STUDY OF OXIDATIVE STRESS MARKERS IN DIABETIC AND NON DIABETIC PATIENTS WITH CATARACT

*Dr. Sunayana Bhat and Dr. Vinay P. G.

Abstract

Purpose: This study compared the relationship of Malondialdehyde(MDA-a marker of oxidative stress) and Glutathione (GSH-which is a natural antioxidant) levels in blood and lens between diabetic patients with cataract and non-diabetic patients with cataract. Methods: In a prospective comparative study Blood and lens samples from thirty patients with diabetes and thirty patients without diabetes undergoing cataract surgery were collected and the levels of MDA and GSH were measured and compared and correlated. Results: There was significant increase in MDA levels in lens and blood in diabetic cataract patients. Levels of GSH in lens and blood were significantly lower in diabetic cataract patients.(p value

Keywords: diabetes, cataract, oxidative stress.