Abstract

AGONIST STUDY OF PHYTOLIGANDS OF C.IGNEUS TARGETED AGAINST ENZYMES OF ANTIOXIDANT DEFENCE SYSTEM

Rohan Pawar, Aditi Rane and Dr. Rekha Dhamnaskar*

Abstract

Inherent defence mechanisms are effective in keeping a variety of pathogens and metabolic irregularities at bay. An analomous behaviour therefore is bound to be scrutinized by the system and dealt with accordingly. In case of oxidative stress, the antioxidant enzymatic system shoulders most of the work. Phytocompounds are gaining unprecedented recognition for their impact in complementary beneficial properties. In this research endeavour, we have performed insilico studies to test agonist nature of Phytol, Benzoqinoline and γ – Tocopherol against SOD, CAT and GPX.

Keywords: Oxidative stress, Phytochemicals, Molecular docking, Antioxidant enzymes.