Abstract

A REVIEW ARTICLE ON CORONA VIRUS (SARS-CoV-2)

*Sarvesh Manoj Jadhav, Hrishikesh Tryambak Kadam, Piyush Anil Boraste and Dr. Ashish Pawar

Abstract

Despite advances in drug discovery, viral infections remain a major challenge for scientists across the globe. The recent pandemic of COVID-19 (coronavirus disease 2019), caused by a viral infection with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has created a disastrous situation all over the world. As no drugs are available to treat this life-threatening disease and the mortality rate due to COVID-19 is high, there is an utmost need to attempt to treat the infection using drug repurposing. Patient shows various symptoms like as fever, cough, sore throat, breathlessness, fatigue etc. The disease is being cured by general treatment, symptomatic treatment by using oxygen therapy and by the immune system. This article emphasizes possible drug candidates in the treatment of COVID-19. Most of these drugs were found to be effective in in vitro studies. There is a need to re-assess in vitro data and to carry out randomised clinical trials. Further investigations of these drugs are recommended on a priority basis.

Keywords: COVID-19, SARS-CoV-2, Drug repurposing, Coronavirus.