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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

A STUDY ON THE SAFETY PROFILE OF PERMETHRIN 5% IN INFANTS LESS THAN 6 MONTHS

Dr. Sukhmani Kaur Brar, Dr. B. K. Brar and *Dr. Neerja Puri

Abstract

Introduction: Scabies is an infectious disease seen commonly in infants and children. Various topical agents have been tried in infants, but safety is an important concern. Aims: To study the side effect profile of permethrin 5% cream in infants between 2-6 months of age. Methods: 30 infants of 2-6 months of age having scabies were selected & were given single night application (6 – 8 hrs) of permethrin 5% cream. Results: Out of 30 cases, only 3 (10%) cases had mild to moderate irritation. no case was seen having any neurological or any other cutaneous side effects on six months of follow up. Discussion: Topical permethrin (5% cream) is a safe and effective scabicide in children and is recommended as a first-line therapy for infants.

Keywords: Scabies; infants; permethrin; topical; infection.


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