Abstract

QUANTITATIVE DETERMINATION AND STANDARDIZATION OF ELECTROLYTES BY INDUCTIVELY COUPLED PLASMA MASSSPECTROMETRY (ICP-MS) FROM BLOOD PRESSURE CONTROLLER CAPSULE

Raju P. Suryawanshi* and Prafullachandra P. Tekale

Abstract

B.P.C. (Blood Pressure Controller) Capsule is one of the most popular herbal medicines in Indian market for Blood Pressure patients. It contains Electrolytes, Trace elements, Toxic, Essential, Trace metals, Minerals, Alkaloids, Steroids and organic compounds, enzymes, proteins and other Inorganic elements like Calcium and manganese, which are naturally present in herbal medicines. The B.P.C. Capsule contain, Calcium (Ca). Manganese (Mn). Though they are essential elements, it is utmost necessary to determine the quantitatively because it affects mostly kidney and blood pressure. The daily requirements of Ca and Mn is in micrograms. It is necessary to establish an accurate, precise, and easy method to detect these elements from herbal formulations. Popularity of herbal medicines is growing worldwide because of their minimal side effects. Herbal medicines required standardization, with implementation and constant review of technical standards of production and effective quality control methods. It is necessary to promote this study in the view of the importance of results of both individual and social field. Diseases occur due to their deficiency and toxicity due to overdose. These Elements can bind to vital cellular components and interfere with their normal functions. Human being, these elements can cause severe physiological and health effects. Therefore, it is necessary to check the efficacy and standardize the levels of these elements in terms of their values. These Elements can be determined quantitatively and validated by using modern technique such as ICP-MS (Inductively Coupled Plasma Mass-Spectrometry)

Keywords: B. P. C. Capsule, Standardization, Herbal medicine, Standardization, ICP-MS, Calcium (Ca), Manganese (Mn).