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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

COMPARISON OF POSTOPERATIVE NAUSEA AND VOMITING AFTER INTRAVASCULAR PATIENT-CONTROL ANALGESIA (PCA) WITH (PARACETAMOL+MORPHINE) AND (PARACETAMOL+ TRAMADOL) IN ORTHOPEDIC SURGERY

Kaveh Behaeen*, Naser Sarrafan, Sholeh Nesioonpour, Mansoor Soltanzadeh,Tahmineh Ghalami

Abstract

Introduction: Postoperative nausea and vomiting is common complications after orthopedic surgery. We compared incidence of nausea and vomiting after hip and femoral surgery. Methods: In a double blind clinical trial study 36 patients in three equal groups randomly, take three methods for controlling post-operative pain. Group C (n=12) control group received intramuscular NSAID (diclofenac 100mg) as routine plan for pain control in orthopedic ward. Group M and T received intravascular analgesic with PCA device in two different combination. Group M (paracetamol 2g+morphine 10mg), group T (paracetamol 2g+ tramadol 100mg) Results: Demographics and statistical data showed post-operative nausea and vomiting (PONV) in three groups was 2 in group C and 1in group M and 4 in group T (P value< 0.05). Conclusion: Incidence of nausea and vomiting with (paracetamol 2g+morphine 10mg) in group M was significant lower than two other groups.

Keywords: morphine - PCA – tramadol – Nausea - pracetamol – Vomiting.


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