Abstract

PREPARATION AND CHARACTERIZATION OF ANTIGENS AGAINST ISOLATED Shigella spp FROM INFECTED STOOL SAMPLES

Dr. Mahenthiran R.*, Sudharsan K., Sornambiga Ravi, Archana S. Nair, Vishnu Priyanka K. and Poovendiran P.

Abstract

Shigellosis, also known as bacillary dysentery or Shigella dysentery, is an enteric bacterial infection caused by a group of Shigella spp. Nowadays, shigellosis is still a major health problem in many parts of world, especially in the developing countries. Bacteria of the genus Shigella spp are human pathogens that infect the gastro-intestinal tract and cause acute shigellosis. Shigella spp are Gram-negative, nonmotile, facultative anaerobic pathogens that are closely related to Escherichia coli but have evolved specific traits of pathogenicity, physiology and serology. Shigella flexnari strains were isolated and characterized by various isolation and identification methods.

Keywords: Shigella spp, ELISA, IgY.