Abstract

PREPARATION, ELEMENTAL ANALYSIS, IR, 1HNMR, UV-VISIBLE CHARACTERIZATION AND MICROBIAL EVALUATION OF Cu(II), Co(II). Ni(II), Mn(II), Cd(II) AND Hg(II) COMPLEXES DERIVED FROM SCHIFF'S BASE

Basavaraj A. Kaloji and Kashinath G. Kanaje*

Abstract

A chiral Mannich base, [1-((2-hydroxyphenyl)(piperidin-1- yl)methyl)thiourea] was prepared by treating with 2-hydroxy benzaldehyde, piperidine and thiourea. Using the above Schiff’s base ligand, the metal complexes of Cu(II), Co(II). Ni(II), Mn(II), Cd(II) and Hg(II) were prepared. Schiff’s base ligand and its metal complexes were characterized by physical methods such as elemental analysis, melting point, TLC, and spectral method such as IR, 1H NMR, UVVisible, ESR studies. For the complexes, molar conductivity and Magnetic susceptibility were also been carried out. The electronic spectra, elemental analysis and magnetic moment results proved that the complexes adopted octahedral geometry. The conductance measurement showed that the complexes are non electrolytes proving their nonionic nature. The synthesized Schiff's base and its metal complexes were tested for their antifungal and antibacterial activity.

Keywords: Piperidine, Thiourea, IR, 1H NMR, UV-Visible and Microbial activity.