Abstract

PHYTOCHEMICAL SCREENING AND ANTI INFLAMMATORYACTIVITY OF ETHANOLIC LEAF EXTRACT OF VITIS VINIFERA

Sabella Venkata Prasanna*, Purilla Salomi*, Rayadurgam Naveen*, Challa Haritha*, Durgesam Ramya*

Abstract

Vitis is the genus in which the Indian medical shrub Grapes (Vitis vinifera) is included, which have been reported to have Phytochemicals and anti-inflammatory effect. Vitis vinifera is hermaphrodite in nature. In the present study the effects of ethanolic extract of Vitis vinifera on pharmacological changes of Albino rats in normal and pain and inflammation induced rats was investigated. The animals were divided into 3 group’s control, low dose (75mg/kg) and high dose (150mg/kg). Rats in each of these groups were sub divided into 2 groups i.e., with inflammation and without inflammation. The rats of each group were tested by injection of Carrageenan and inflammation in rats treated with Vitis vinnifera extract when compared with control group.

Keywords: Vitis vinnifera, phytochemical screening, ethanolic extract, Inflammation, carrageenan.