Abstract

CLINICAL PROFILE AND OUTCOMES OF ACUTE KIDNEY INJURY PATIENTS IN WARANGAL REGION-DESCRIPTIVE STUDY

A. Suma, R. Deepthi*, P. Kishore and D. Sudheer Kumar

Abstract

Aim: To study the clinical profile, management and clinical outcomes in acute kidney injury patients. Method: A descriptive study (Vishwas Superspeciality Hospital and Dialysis Centre, Chowrastha, Hanamkonda) carried out for a period of 6 months i.e. from July 2019 to Jan 2020 by involving all patients from nephrology department, who arediagnosed with Acute kidney Injury. Results: Out of200 patients, highest prevalence of AKI was observed in the age group between 51- 60 years (28.9 5) and males (64 %) were predominant. The number of patients with a history of drinking alcohol, smoking and both was 28.5%, 7 %, and 20.5 %, respectively. Comorbidities were present in 58.5 %, with hypertension (19.65 %), diabetes mellitus (14.52 %) and DM+HTN (47.86 %) being the most common. Fever was the most common (68.5 %) presenting symptom, followed by oliguria (63 %). The most common cause of AKI was Sepsis (39 %). Prerenal, renal and postrenal causes occurred in 124 (62 %), 48(24 %) and 28 (14 %) patients, respectively. 46 % had stage I, 30 % had stage II and 24 % had stage III. AKI was attenuated by metabolic acidosis and cumulative fluid balance. Mean serum creatinine levels of stage I, II, III before treatment were 1.7, 2.9 and 5.7, respectively. Mean serum creatinine levels of stage I, II, III after treatment 1.2, 1.8 and 3.8, respectively. Mean blood urea levels of stage I, II, III before treatment were 37.1, 73.4, and 113.5, respectively. Mean blood urea levels of stage I, II, III after treatment decreased to 23.1, 43.7, and 63.8, respectively. The majority (71 %) of patients received conservative treatment with average duration of hospital stay between 3-9 days. After treatment, the majority of patients achieved partial recovery 46.5 %. Conclusion: This study demonstrated about clinical profile and outcomes in acute kidney injury patients in nephrology department.

Keywords: AKI (Acute Kidney Failure), CKD (Chronic Kidney Disease), KDIGO Kidney Disease Improving Global Outcomes, SCr (Serum Creatinine), Electrolyte imblanace, Diuerisis.