Abstract

STUDY OF ASSOCIATED RISK FACTORS IN PATIENTS WITH ACUTE ST ELEVATION MYOCARDIAL INFRACTION AND COMPLICATIONS OF STREPTOKINASE THERAPY

Ms. Vishakha Mewade*, Mr. Zuber Chaudhary and Ms. Saraswati Thore

Abstract

The aim of current work was to evaluate the adverse drug reaction (ADRs) induced by streptokinase and its related risk factors in acute ST elevation MI (STEMI) patient. In the present study period, 129 patients were taken for study who received streptokinase. The majority of patients (n = 125) were occur ADR and because of cardiac causes out of 129 patients 10 patients were died in-hospital. The most serious ADR was paralysis n= 24(7%) dyspnea = 12 (3%), hemiplegia n = 9(3%), aphasia n= 6(2%), and abdominal pain n = 56(16%). It is concluded that the history of smoking is the main risk occurring acute MI also higher rate of abdominal pain was related to streptokinase therapy in Indian population.

Keywords: Streptrokinase, Adverse drug reaction, ST elevation myocardial infraction, Risk factors, myocardial infraction.