Abstract

3D PRINTING OF PHARMACEUTICAL DRUG DELIVERY SYSTEM: CHALLANGES AND APPLICATIONS

Abhishek Singh*

Abstract

Three-dimensional printing (3DP) is a unique technique for prototyping that has evolved over the past 35 years and has the tremendous potential to revolutionise the field of therapeutics with its inherent advantages of configurability and the ability to manufacture highly precise and accurate complex solid dosage types. With variable densities and diffusivity, 3DP can generate strong dosage types, complex internal symmetries, numerous drugs and excipients. Literature results reveal many benefits of 3DP technology over existing approaches in the area of innovative drug delivery systems (NDDS). The drug distribution problems of poorly water-soluble medications, peptides, potent drugs and multi-drug release, etc can be easily solved by 3DP. However, the use of 3DP in the consumer industry is limited by issues such as the selection of suitable binders, excipients and mediated gene properties of final products. Further improvement in process quality is required to solve these issues, where 3DP technology can be efficiently paired with NDDSS. Here, we present an overview of the development of emerging drug delivery technologies and the promise of 3DP.

Keywords: New drug delivery system, customised medicine, new drug delivery, threedimensional printing.