ORAL SUBMUCOUS FIBROSIS – A LITERARY REVIEW ACCORDING TO MODERN SCIENCES AND AYURVEDA.
Dr. Shubhangi Suresh Avhad and Dr. Chandana Abhay Virkar
Abstract
Oral submucous fibrosis is a precancerous disease of oral mucosa
predominantly found in India and few other Asian countries as a result
of chewing areca nut and its byproducts. It is characterized by juxta
epithelial inflammatory reaction and progressive fibrosis of
submucosal tissues of oral cavity and sometimes pharynx. Symptoms
include burning sensation, ulcerations, xerostomia, vesicle formation,
fibrosis, difficulty in opening mouth and malignancy of oral cavity in
some cases which greatly affects patient’s quality of life. Arecoline
found in betel nut increases the formation of collagen which leads to
fibrosis. Deficiencies of micronutrients also play important role in
development of the disease. Acharya Sushruta has described similar
symptoms in Sarvasar Mukharoga which means diseases of oral cavity.
Treatment for this disease is stoppage of chewing habits, avoiding irritants, nutritional
supplements, oral hygiene and steroids. This article gives a brief modern and Ayurvedic
review of etiopathogenesis, clinical features, treatment, preventive measures of Oral
Submucous Fibrosis.
Keywords: areca nut, collagen deposition, hypoxia, trismus, fibrosis, sarvasar mukharoga.
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