Abstract

ORGANOGEL: AN IDEAL DRUG DELIVERY CARRIER

Jisu Das*, Bedanta Bhattacharjee, Jagya Jyoti Dutta and Tirna Paul

Abstract

Organogels are semi-solid systems in which a three-dimensional network of self-assembled, interlaced gelator fibers immobilizes an organic liquid phase. Despite having a mostly liquid composition, these systems exhibit a solid-like appearance and rheological behavior. They are employed as drug and vaccine delivery systems in pharmacology, with active components delivered via transdermal, oral, and parenteral routes. Unfortunately, the toxicity of the selected organic solvents has impeded their usage as medication delivery methods in the past. More biocompatible organogels have recently been synthesized, which has aided the development of numerous biological and pharmacological applications. This article seeks to provide a comprehensive overview of organogels, with a focus on the types, characterization, preparation, and the use of organogels as drug delivery platforms for active agent administration via various routes such as transdermal, oral, and parenteral is then discussed.

Keywords: Organogels, Rheological, Biocompatible, Drug delivery.