Abstract

A REVIEW ON CORONA VIRUS (COVID-19)

Bhavana Dnyandeo Tambe*, Shraddha D. Tambe, Aarti D. Tambe, Prasad D. Tambe, Gaurav V. Tambe, Kartik V. Tambe and Sarika V. Tambe

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Abstract

The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. The intermediate source of origin and transfer to humans is not known, however, the rapid human to human transfer has been confirmed widely. Coronaviruses are a group of enveloped viruses with nonsegmented, single-stranded, and positive-sense RNA genomes. Apart from infecting a variety of economically important vertebrates (Such as pigs and chickens), six coronaviruses have been known to infect human hosts and cause respiratory diseases. Among them, severe acute respiratory syndrome coronavirus (SARSCoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) are zoonotic and highly pathogenic coronaviruses that have resulted in regional and global outbreaks Coronaviruses possess a distinctive morphology, the name being derived from the outer fringe, or ―corona of embedded envelope protein. Members of the family Coronaviridae cause a broad spectrum of animal and human diseases.

Keywords: Corona, Respiratory, Pathogenesis; Emergency; Pandemic.