Abstract

A REVIEW ON NANONIOSOMES

Nasrina Abdin*, Bidisha Bordoloi, Toufikananda Rabha and Jagya Jyoti Dutta

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Abstract

Drug delivery systems are the formulations targeting for transport of a drug to the area desired for the action within the body. The field of nanochemistry research has revealed a great advancement in the emerging of novel nanocarriers as potential drug delivery systems. The current review discusses about the most important features of niosomes like their types, the diverse preparation approaches, advantages, their stability, their uses, their therapeutic applications. The unique structure of niosome presents an effective novel drug delivery system (NDDS) with ability of loading both hydrophilic and lipophilic drugs. The low cost of manufacture, ingredients, stability, possibility of large-scale production, and the resultant ease of storing of niosomes have led to the exploitation of these nano carriers as substitutes to other micro and nano-encapsulation technologies. In past niosomes were used in cosmetics & it has applications on therapy of cancer, used as a carrier in haemoglobin, transport of the peptide drugs orally, in leishmaniasis, in cosmetics and as carrier in dermal drug delivery. Abundant research articles were published in scientific journals, reporting valuable results of individual case studies in this context. The present review describes preparation methods and recent studies on niosomal drug delivery systems and also gives up to date information regarding recent applications of niosomes in drug delivery.

Keywords: Niosomes, hydrophilic drugs, production, drug delivery system.