Abstract

A COMPREHENSIVE REVIEW ON: PREPARATION OF FAST DISSOLVING TABLETS, CHARACTERIZATION, OPTIMIZATION AND EVALUATION

Ganesh Lal*, Satyanand Mourya, Roshan Kumar Dubey and Dr. Abhishek Kumar

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Abstract

The mouth is the most used route for administration of medication because of it's very cost-effective, safest and most convenient advantages. Previously Schere RP, developed the first lyophilized fastdissolving technology Zydis in 1986, & since then, there has been a steady increase in patented technique, technique, names, & by other businesses like oraquick technology and Wowtab technique. Super disintegrants such as Croscarmellose Sodium, Crospovidone (CP), PVP and Sodium Sarch Glycolate (SSG), as binders are among the excipients used in the composition. The Fast Dissolving Tablet (FDT) was recently created by researchers to enhance sufferer convenience and compliance. FDTs are solids that melts quickly in mouth with no need of chewing or extra H2O. FDTs address the drawbacks of traditional dose forms, particularly dysphagia in juvenile & elderly people. There are many quick-dispersing Rx & OTC medicines on the market today, the majority of which were introduced in the last three to four years. The number of novel chemical compounds under research utilizing a quick- dissolving medicine delivery method has also increased significantly. As a result, it is anticipated that in the not-too-distant future, this distribution method will be as important as traditional delivery methods. This study covers ideal formulation, difficulties, features, characteristics, drug candidate eligibility, patented techniques, different FDT techniques, assessment techniques, patented techniques and numerous commercial products.

Keywords: Drug delivery system, Fast dissolving tablets, Super disintegrants, fast disintegrating, fast melting.