Abstract

INVESTIGATION OF QUERCUS INFECTORIA OLIVIER GALLS FOR ANTI-ARTHRITIC ACTIVITY

*Ameena Farhath, Meera Bhaskaran, Snesha S. R., Riyama Shirin V. K., Mohammed Favas O. A.

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Abstract

We investigated the ethanolic and aqueous extract of Quercus infectoria Olivier galls (local names: aleppo oak, majuphal, manjakani, masikai, maayaaphala) collected from the local market of Calicut for its anti-arthritic activity. The anti-arthritic activity was determined using various assays which include inhibition of protein denaturation, effect on membrane stabilization and proteinase inhibitory action. The ethanolic extract of Quercus infectoria gall showed a higher activity of inhibition of protein (bovine serum albumin) denaturation (58.1%), HRBC membrane stabilization (70.9%) and proteinase inhibitory action (52%) at a concentration of 100μl. Overall, the ethanolic extract had higher anti-arthritic activity than in the aqueous extract. We conclude that the Quercus infectoria galls investigated in this study are useful in the treatment of arthritis.

Keywords: Arthritis, Quercus infectoria, Gall, Ethanolic extract.