Abstract

CLINICAL USES OF PIPERINE: A REVIEW

Gurpreet Bawa*, Navneet Khurana and Ayush Singh

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Abstract

Main Substance of piper nigrum is Piperine having pungency that is accountable for hundreds of clinical dietary utility and worldwide popularity as a food ingredient. It is act as a edible ingredients and utilized as a edible preservations with the application, that is utilized in the conventionally drug for various demonstrations, that assured in various modern investigations on its biological effects. Conformations that piper nigrum constitutents have various biological active efficacy such as chemotherapeutical actions with their physiological effect that can donate to general human health, including immunomodulatory, liver protectives agents, antioxidant, antimetastatic, antitumor, and many other activities. Human investigations elaborates that the antioxidant, antitumor, and pharmaceutical doses availability-increased their functioning of this substance along with potency of immunomodulatory. These factors to the uses of potency of piper nigrum and need to incorporate this compound into general health incremented pharmaceutical dose, as well as into those that would be utilization as adjunctive therapy in order to incremented the absorption rate of different (chemo) therapeutic pharmaceutical.

Keywords: Piperine; Bioactivity; Clinical studies; Bioavailability of drugs.