Abstract

BIOLOGICAL ACTIVITY DETERMINATION OF HUMAN MENOPAUSAL GONADOTROPIN IN WISTAR RATS

K. Sri Devi* and Ch. S. A. Gowthami

.

Abstract

Human menopausal gonadotropin (HMGs, or menotropin) are a combination of FSH and LH in 1:1 ratio i.e., extracted from urine obtained from post menopausal women.HCG contains large quantities of LH with little FSH it is secreted by placenta an extracted from the urine of pregnant women. HMG is a medication i.e., composed of FSH with LH and is used for stimulation of egg development in women who do not ovulate spontaneously, who ovulate extremely irregularly, or to increase the number of eggs developed in a single cycle in women who already ovulate. FSH is fundamentals for follicular recruitment in the first stages of folliculogenesis and is involved in physiological events that promote the growth of an appropriate pre ovulatory follicle in the last stages of folliculogenesis.

Keywords: HMG, FSH, LH.