Abstract

NANOSPONGES AN ADVANCE TECHNIQUE OF DRUG DELIVERY SYSTEM: A REVIEW

*Robina Jidung, Bhupen Kalita, Trishna Das, Kamallochan Barman, Mayuri Phukan

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Abstract

The invention of nanosponge is a significant step in the history of medical sciences. It has thoroughly overcome many of the problems that our traditional system has faced. Apart from the effective drug delivery, which was a dream for a long time, it has also help in cancer and other deadly diseases by the means of its accurate and targeted drug delivery. Researches have also proven that it is going to become one of the major assets in present scenario for overcoming the SARS-CoV-2 virus. Nanosponges are microscopic sponges around the size of a virus that can be filled with a variety of medications. In a typical drug delivery for a particular site using nanosponges, the sponge circulates around the body until they interact with specific target site and thereby release drug in a controlled manner. The aqueous solubility of nanosponges is one of their most important properties; this allows these systems to be used efficiently for medications with low solubility. The present review highlights the Origin of nanosponges along with their structure, the method of preparation along with the factors influencing nanosponge preparation and their potential applications.

Keywords: nanosponge, drug delivery, SARS-COV-2, solubility.