Abstract

A REVIEW ON PHARMACOGENOMICS

Priyanshi Monpara*, Dhruvi Kasvala, Prof. Pooja Patel and Dr. Umesh Upadhyay

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Abstract

Pharmacogenetics and pharmacogenomics are two new fields of study that have a lot of potential in medication discovery and therapy. It improves personalised therapy and provides a critical method for patients with medication response variability due to hereditary, promoting personalised medicine. Pharmacogenomics aims to create reasonable methods for improving medication therapy based on a patient's genotype in order to enhance efficacy while reducing adverse drug effects. It has the potential to transform medical practise and usher in a new era of customised medicine, in which pharmaceuticals and drug combinations are tailored to each individual's genetic composition. On the other side, it is the process of using genetic information from a population or an individual to predict the safety, toxicity, and efficacy of medications, either as part of a drug development programme or as part of an individual's diagnosis and treatment plan. Pharmacogenomics is a field of pharmacology that studies the impact of genetic variation on drug response in patients by linking gene expression and single-nucleotide polymorphisms to therapeutic efficacy and toxicity. Its goal is to come up with sensible ways to optimise drug therapy based on a patient's genotype, ensuring optimal efficacy with minimal side effects. Such approaches herald the arrival of 'personalised medicine,' in which medications and drug combinations are tailored to each person's unique genetic profile. Pharmacogenomics is a type of pharmacogenetics that analyses single gene interactions with medications across the entire genome.

Keywords: Genetics; Pharmacogenetics; Pharmacogenomics; Personalized Medicine; Drug Development; Therapeutics.