Abstract

PLANT BASED EDIBLE VACCINES: A REVIEW

Isha R. Jain, Nazma M. Ansari, Rushikesh S. Shingi, Sanjay G. Walode and Vibhavari M. Chatur*

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Abstract

Plant-based Edible vaccines are cost effective, easy to administer, storable and widely acceptable as a vaccine delivery system especially in the poor developing countries. Human trials conducted by the National Institute of Allergy and Infectious Diseases (NIAID), US Department of Health and Human Services, USA show that edible vaccines are feasible. Prodi Gene, a biotech company, has a patent for vaccine against, viral diseases of hepatitis and transmissible gastroenteritis virus. Plant-based Edible vaccines are subunit vaccines that introduce selected genes into the plants and facilitate the production of encoded protein. Plant-based Edible vaccines are currently being developed for number of human and animal diseases. There is an increasing demand of transgenic crops in both industrial and developing countries. This review is focused on the conception of plant based edible vaccines along with mechanism and production of plant based edible vaccines.

Keywords: Plant-based Edible vaccine, transgenic crops, mucosal targeted vaccines, plant expression host.