Abstract

A COMPREHENSIVE REVIEW: ANTIBIOTICS FROM MARINE ORIGIN AS PROMISING SOURCE

Rutuja S. Dhaigude, Pragati D. Kale, Tejasvi S. Jadhav and Sukanya P. Paricharak*

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Abstract

In recent years two producers of marine derived antibiotics isolated from deep sea habitat from the surface of marine invertebrates and algae. Antibiotics are extremely important in fight against infections. There is also increasing problem of antimicrobial resistance. That is why appropriate use of antibiotics is great importance. Antibiotic is an essential part of modern medicine. This review covers marine drugs used for antibiotics. The increasing emergence of new forms of multidrug resistance among human pathogenic bacteria, coupled with the consequent increase of infectious diseases, urgently required the discovery and development of novel antimicrobial drug with new mode of action. Members of each class of metabolite- ribosomal and non- ribosomal peptides, alkaloid, polyketides and terpenes they show antibacterial activity. It is marine world that will provide the Pharmaceutical industry with the next generation of antibiotics. Marine antibiotics are antibiotic obtained from the marine organism. The discovery of various antibiotic from marine bacteria. In review, various antibiotic obtained from marine microorganism, also its classification, discovery and development, Problem arises with the use of AMS, failure of use of AMA (chemotherapy). Need for this topic is very important. The concerted effort to discover new antibacterials from marine sources has the potential to contribute significantly to the treatment of ever increasing drug- resistant infectious disease. The present article provide an overview of various antibiotics obtained from marine sources.

Keywords: Marine bacteria, antibiotics, antibacterial activity, antibiotic resistance, antibiotic from deep sea microorganisms, AMA(chemotherapy).