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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

MALIGNANT TUMORS WITH PARASITES

Ragaa Issa*

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Abstract

Background: Certain parasites that can live inside the human body can also raise the risk of developing some kinds of cancer. Several parasites infest liver or biliary tree, either during their maturation stages or as adult worms. Multiple factors can significantly contribute to carcinogensis. Material and Methods: Parasitic pathogens and infection associated malignancy may be blood flukes, liver flukes, plasmodia species, strongyloides stercoralis, trypanosome curizi and sometime intracellular protozoan parasites like leishmania and toxoplasma gondii. Results: Adult worms are usually found in human hosts; their interactions with the host and parasite-derived products including their eggs strongly induce carcinogenesis. These malignancies included basal cell carcinoma, squamous cell carcinoma, and lymphoma. Although some parasitic infections have been very strongly associated with specific cancers, the available reported data have potentially linked leishmaniasis infection with the development of malignancy in humans and in animals. Conclusion: Although there are some parasites itself is not classified carcinogenic, but their risk more than the cancers as leishmaniasis, toxoplasmosis, amebiasis, hydatid cysts and fasciola hepatica.

Keywords: tumors, liver flukes, blood flukes, parasites, schistosomiasis, strongyloides, plasmoides, trypanosome curizi, leishmaniasis, toxoplasmosis, amebiasis, carcinoma, and lymphoma.


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