Abstract

INFLUENCE OF INTERLEUKIN-17 IN PERIODONTITIS

K. Vijay Kumar*, K. Malathi and N. Srividya

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Abstract

Cytokines are protein cells that are involved in a variety of physiological responses. They have a picomolar concentration of action and are exceedingly powerful. Physiological and pathological tissue remodelling, haematopoiesis, angiogenesis, and wound healing are all regulated by individual cytokines. It binds to cell surface receptors with a high affinity for them. The type of cell, local concentrations, and other cell regulatory factors to which it is constantly exposed determine a cell's response to a given cytokine. The IL-17A isoform (also known as IL-17) is involved in nearly all IL-17-related studies in the field of periodontal disease. To comprehend the significance of IL-17 in periodontitis, it is necessary to first review the cytokines basic biology and the cells that form it. Because of its role in inflammatory disease, IL-17 is one of the most well studied cytokines in immunology. The aim of this review is to know the role of IL-17 in periodontal disease.

Keywords: Cytokine, Basics biology of Interleukin-17, Periodontal disease, Complement and IL-17, Neutrophil homeostasis.