Abstract

ORALLY DISINTEGRATING FILM: A REVIEW

Ankita Pokhriyal* and Geetika Tripathi

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Abstract

Buccal drug delivery has become an important route of drug administration. Various bioadheshive mucosal dosage forms have been developed, which include adhesive tablet, gel, patch, and more recently films were developed. Oral route is used for the administration of various dosage forms such as orally disintegrating tablets, films, patches, wafers, chewing gums etc. A strip or film can be defined as a dosage form that employs a water dissolving polymer (generally hydrocolloid, which may be a bio adhesive polymer), which allows the dosage form to quickly hydrate, adhere and dissolve when placed on the tongue or oral cavity (i.e. buccal, palatal, gingival, lingual or sublingual, etc.) to provide rapid local or systemic drug delivery. The orally disintegrating films can be administered in the oral cavity and disintegrates within a second to give better therapeutic action. In this article we discuss about the orally disintegrating film, its preparation and evaluation parameters.

Keywords: Buccal drug delivery, orally disintegrating film, oral dosage form, oral route.