Abstract

MYASTHENIA GRAVIS (MG) IS AN "AUTOIMMUNE DISEASE": A REVIEW

Mayuri Thorat*, Gauri Tambe, Komal Sargar and Vaishnavi Patil

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Abstract

Myasthenia Gravis (MG) is a immunological disorder which caused due by weakness and fatigability of voluntary muscles. Myasthenia is caused by a decrease in the number of postsynaptic acetylcholine receptor at the neuromuscular junction, which decreases the capacity of the neuromuscular end plate to transmit the impetus. Myasthenia Gravis (MG) was recognized as a clinical entity in 17th century. History is mention it. Epidemiology the prevalence of myasthenia gravis in pregnancy is estimated at 1in 20, 000 pathophysiology of Myasthenia Gravis is autoantibodies against acetylcholine receptor. The review is an hardwork to collect these classfication, treatment, and diagnostic test of Myasthenia Gravis in an huge information the literature on (MG).

Keywords: Myasthenia Gravis, Autoantibodies, Epidemiology, Neuromuscular junction, Weakness, fatigue, Thymectomy, acetylcholine esterase inhibitors, immunosuppresant, Immune modulation.